Autores/as

  • M. Sanchis Fortea Médico Jefe Clínico Unidad Desintoxicación Hospitalaria Bétera (Valencia).
  • J. Cuevas Badenes Médico Responsable Unidad Alcohología. Valencia.
  • Mª A. Sanchis Arnau Lcta. Farmacia. Valencia.

DOI:

https://doi.org/10.20882/adicciones.600

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Abdulla, A.; Badawy, B. (1979): “El metabolismo del alcohol”. En: Marks, Wright, Directs. Clínica Endocrinológica: Efectos Metabólicos del Alcohol. Salvat Editores. Barcelona. pp:1-24.

Agarwal, D.P.(1997): “Molecular genetic aspects of alcohol metabolism and alcoholism”. Pharmacopsych., 30, 79-84.

Agarwal, D.P.(1998): “Pharmacokinetic and pharmacogenetic aspects of alcohol.” In: Snel, Lorist, Eds., Nicotine, Caffeine and Social Drinking. The Nederlands: Harwood. pp:259-274.

Albano, E.; Dianzini, M.U. (1996): “Role of free radicals in alcohol-induced liver damage.” Alcologia, 8, 79-84.

Ameno, N. et al. (1998): “DRAI site polymorphism of the human CYP2E1 (Cytochrome P4502E1) gene and alcoholism.” 9th ISBRA CONGRESS.Copenhagen, Denmark.

Aragon, C.M.G.; Spivak, K.; Amit, Z. (1985): “Blockage of ethanol induced condicioned taste aversion by 3-amino, 1,2,4 triazole: Evidence for catalase mediated synthesis of acethaldehyde in rat brain” Life Sciences, 37, 2077-2084.

Aragon, C.M.G.; Stoland, L.M.; Amit, Z. (1991): “Studies on ethanol-brain catalase interaction: Evidence for central ethanol oxidation.” Alcoholism: Clin. Exp. Res.,15, 165-169.

Asai, H. et al. (1996): “Microsomal ethanol oxidizing system activity by human hepatic cytochrome P450s.” J. Pharmac. Exper. Therap., 277, 1004-1009.

Bode, J. C.(1980): “Alcohol and the gastrointestinal tract” Advanc. Intern. Med. Pediat.,45, 1-75.

Bonnichsen, R.K.; Wassen, A.M. (1948): “Crystalline alcohol dehydrogenase from horse liver”. Arch. Biochem. Biophys., 18, 361.

Boveris, A.G. et al. (1972): “The cellular production of hydrogen peroxide” Biochem. J., 128, 617-630.

Bower B. (1986): “Researchers tackle the mystery of alcoholism.” New Physician, 35, 26-28, 42-43.

Carr, L.G. et al.(1996): “Failure to find exon 7 polymorphism in the ADH7 gene in Chinese, Japanese, African-Americans, and Caucasians.” Alcoholism: Clin. Exper. Res., 20, 418-419.

Chao, Y.C. (1997): “ Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients”. Hepatology, 25, 112-117.

Chrostek, L.,Szmitkowski, M.(1998): “ Genetic evaluation of tolerance to alcohol”. Postepy Hig. Med. Dosw., 52, 35-47.

Cohen, P.A. et al. (1997): “Immunohistochemical determination of hepatic cytochrome P-4502E1 in formalin-fixed, paraffin-embedded sections.” Alcoholism: Clin. Exper. Res., 21, 1052-1062.

Conney, A.H.(1967): “Pharmacological implications of microsomal enzyme induction.” Pharmac. Reviews, 19, 317-366.

Correa, M. et al. (1998): “Acute lead administration potentiates ethanol- induced locomotor activity: the involvement of brain catalase.” 9th ISBRA CONGRESS. Copenhagen, Denmark.

Correa, M. et al. (1998): “Lead acetate and 3-amino-1,2,4-triazole on brain catalase and ethanol- induced locomotor activity”. 9th ISBRA CONGRESS.Copenhagen, Denmark.

Craab, D.W. et al. (1989): “Genotypes for aldehyde dehydrogenase deficiency and alcohol consumption.” J. Clin. Invest., 83, 314-316.

Crabb, D.W.; Edemberg, H.J. (1996): “Gene regulation of alcohol metabolizing enzymes.” Suppl. Alcoholism: Clin Exper. Research, 20, 113-116.

Crow, K.E.; Hardman, M.J. (1989): “In: Crow, Batt Eds.: Human Metabolism of Alcohol” Boca Raton, FL:CRC Press.pp. 3-16.

Davis, G.J. et al. (1996): “X-ray estructure of human beta3 beta3 alcohol dehydrogenase”. J. Biol. Chem., 271, 17057-17061

Doria, J.J. (1997): “Alcohol metabolism”. Alcohol Health & Research World, 21, 323.

Elbel,H., Schleyer, F. (1956): “Blutalkohol. Die Wissenschaftlichen Grundlagen der Beurteilung von Blutalkoholbefinden.” 2 Ed. Thieme,G., Stuttgart.

Engeland, K.; Maret, W. (1993): “Extrahepatic differential expression of four classes of human alcohol dehydrogenase”. Biochem. Bioph. Res. Commun., 193, 47-53.

Fukunaga, T. (1998): “ Evaluation of m-RNA levels for ALDH2 in human peripheral blood before ans after ethanol intake”. 9th ISBRA CONGRESS.Copenhagen, Denmark.

Gentry, R.T.; Baraona, E.; Lieber, C.S. (1994): “Agonist: The case againts first pass metabolism of the ethanol in the stomach.” J.Labor. Clin. Med., 123, 21-26.

Hamby-Mason, R.L. et al. (1997): “Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain.” Alcoholism: Clin. Exp. Res.,21, 1063-1072.

Hamby-Mason, R.L. (1997): “Catalase-mediated production of acetaldehyde as a mechanism underlying ethanolenhanced apoptosis in the developing brain.” Disser. Abs. Intern., 58, 1230-B.

Harada, S. et al. (1985): Alcohol, 2, 391-392.

Harger, R.N., Forney, R.B. (1963): In: Stolman Ed.: Progress in Chemical Toxicology. Academic Press, N. York. Vol 1 p.79.

Hawkins, R.D.; Kalant, H. (1972): “The metabolism of ethanol and its metabolic effects.” Pharmacol. Reviews, 24, 67-167.

Holmes, R.S. (1994): “Alcohol dehydrogenases: a family of iszymes with differential functions”. Alcohol Alcoholism Suppl. 2, 127-130.

Homann N. Et al. (1998): “Acetaldehyde in saliva: formation and pathogenic aspects” 9th ISBRA CONGRESS. Copenhagen, Denmark.

Höög, J.O. et al (1998): “Structure and function of novel forms of mammalian alcohol dehydrogenase.” 9th ISBRA CONGRESS. Copenhagen, Denmark.

Hsu, L.C.; Chang, W:C.(1996): “Sequencial and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family.” Gene, 174, 319-322.

Hunt, W.A, (1996): “Role of acetaldehyde in the actions of ethanol on the brain: A review.” Alcohol: An Inter. Biochem. J., 13, 147-151.

Iwahashi, K. et al. (1996): “CYP2E1, ALDH2 and ADH2 genotypes and blood ethanol elimination kinetics.” Clin. Chim. Acta, 255, 85-87

Jacoby, W.B. (1963): In: Boyer, Lardy, Myrbäck, Eds., In the Enzymes. Academic Press, Inc., New York, pp: 203-211

Julkunen, R.J.K. et al.(1985): “First pass metabolism of ethanol: An important determinant of blood levels after alcohol consumption.” Alcohol, 2, 437-441.

Kalant, H. (1979): “Absortion, Diffusion, Distribution, and Elimination ot Ethanol: Effects on Biological Membranes.” In: Kissin and Begleiter, Eds. The Biology of Alcoholism. Plenum Press. New York. vol 1 pp.1-62.

Keilin, D.; Hartree, E.F. (1936): “Coupled oxidation of alcohol.” Proceed. Roy. Society, 119, 141-159.

Keilin, D.; Hartree, E.F. (1945): “Properties of catalase. Catalysis of coupled oxidation of alcools.” Biochem. J., 39, 293-301.

Kim, R.B. et al. (1996): “In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.” J. Pharm. Exper. Ther., 279, 4-11.

Kitson, K.E.; Weiner, H. (1996): “Ethanol and acetaldehyde metabolism: Past, present, and future”. Suppl. Alcohol: Clin. Exper. Res., 20, 82A-92A.

Kostrubsky, V. E. et al. (1995): “Ethanol and isopentanol increase CYP3A and CYP2E in primary cultures of human hepatocytes.” Archiv.Biochem. Biophys.,322, 516-520.

Lasker, J.M.et al. (1987): “Purification characterization of human liver citocrome P-450-ALC.” Biochem. Biophys. Res. Commun., 148, 232-238.

Levitt, M.D. (1994): “Antagonist: The case againts first pass metabolism of the ethanol in the stomach.” J.Labor. Clin. Med., 123, 28-31.

Lieber, C. S. et al. (1996): “First pass metabolism of ethanol.” In: Saunders, Whitfield Eds. Biology of Alcohol Problems. Seventh ISBRA Congress. Australia. Pergamon Press. New York. pp: 163-169.

Lieber, C. S., DeCarli L.M. (1968): “Hepatic microsomes: a new site for ethanol oxidation.” J. Clin. Invest., 47, 62.

Lieber, C.S. (1994): “Metabolic consequences of ethanol” Endocrinologist, 4, 127-139

Lieber, C.S. (1996): “Metabolism of alcohol and its implications for the pathogenesis of disease”. In: Preedy, Watson Eds.: Alcohol and the Gastrointestinal Tract. Boca Raton, FL:CRC Press. pp. 19-29.

Lieber, C.S. (1997): “Cytochrome P-4502E1: Its physiological and pathological role.” Physiolog.Reviews, 77, 517-544.

Lieber, C.S. (1998): “Biochemical and molecular basis of alcohol induced injured to liver and other tissues.” N. Eng. J. Med., 319, 1630-1650.

Lieber, C.S.(1977): Metabolic aspects of alcoholism. MTP, pp: 1-30.

Lieber, C.S. (1969): “In: Bittar, Ed., “The Biological Basis of Medicine.” Academic Press. London. pp:317-344.

Lieber, C.S. (1988): “Biochemical and molecular basis of alcohol indyced injured to liver and other tissues.” N. Eng.J. Med., 319, 1630-1651.

Liopo, A.V. (1998): “Ethanol metabolism in rat brain: kinetics and regional distribution.” 9th ISBRA CONGRESS. Copenhagen, Denmark.

Long J.C. et al (1998): “Neurogenetics Lab scan suggest genetic linkage on chromosomes 4 and 11”. Neuropsych. Genetics, 81, 3.

Matsushima, T. (1995): “ADH isoenzymes”. Nippon Rinsho, 53, 1237-1240.

Mezey, E. (1985): “Effect of ethanol on intestinal morphology, metabolism and function.” In: Seitz, Kommerell, Eds., Alcohol related diseases in gastroenterology. Berlin: Springer-Verlag.pp 342-360.

Moser et al (1968): “Heterogenität und Organverteilung der Alkoholdehydrogenase bei verschiedenen Spezies.” Enzym. Biol. Clin., 9, 447.

Nakamura, K. et al. (1995): “Association between alcoholics and the genotypes of ALDH2, ADH2, ADH3 as well as P-4502E1.” Japan. J. Stud. Drug. Depend., 30, 33-42.

NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (1997): “Alcohol Metabolism.”. Alcohol Alert, Nº 35, PH 371.

NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (1998): Press: 301/443-3860.

Nebert, D.W. et al. (1987): “The P-450 gene superfamily, recommended nomenclature.” DNA, 6, 1-8.

Negelein, E., Wulff, H.J.(1937): “Diphosphopyridinproteid, Alkohol, Acetaldehyd.” Biochem.Z.293:351.

Nosova, T. et al. (1997): “Characteristics of alcohol dehydrogenases of certain aerobic bacteria representing human colonic flora”. Alcoholism: Clin. Exp. Res.,21, 489-494.

Parés, X. et al (1994): “Genetic polymorphism of liver alcohol dehydrogenase in Spanish subjects: significance of alcohol consumption and liver disease.” Alcohol Alcohol., 29, 701-705.

Parés, X. et al.(1998): “Alcohol Dehydrogenase genotypes in Europeans”. 9th ISBRA CONGRESS.Copenhagen, Denmark.

Pares, X.; Farres, J. (1996): “Alcohol and aldehyde dehydrogenases in intestinal tract.” In: Preedy, Watson, Eds., Alcohol and the Gastrointestinal Tract. Boca Raton, CRC Press.pp: 41-46.

Rajagopalan, K.V.; Handler, P. (1964): “Hepatic aldehyde oxidase.” J. Biol. Chem., 239, 2022-2027.

Rapaka R.S. et al. Eds. (1997): Pharmacokinetics, metabolism and pharmaceutics of drug of abuse. NIDA Research Monograph nº 173. Rockville, MD: NIDA.

Reich, T et al.(1998): “COGA genome scan suggest linkage on chromosomes 1,2,4 and 7” Neuropsych. Genetics, 81, 3.

Rout, U.K. (1992): “Alcohol dehydrogenases in the brain of mice.” Alcoh. Exper. Research, 16, 286-289.

Rubin, E. et al. (1968): “Ethanol increases hepatic smooth endoplasmic reticulum and drug-metabolizing enzymes.” Science, 159, 1469.

Salaspuro, M. (1996): “Bacteriocolonic pathway for ethanol oxidation: Characteristics and implications”. Annals of Medicine, 28, 195-200.

Sate, M.A. et al. (1994): “Complete structure of human class IV alcohol dehydrogenase(retinol dehydrogenase) determined from the ADH7 gene.” J. Biol. Chem., 269, 15606-15612.

Sato, N., Kitamura, T. (1996): “First-pass metabolism of ethanol: An overview” Gastroenterology, 111, 1143-1150.

Seitz, H.K. et al. (1996): “Ethanol metaolism in the gastrointestinal tract and its possible consequences.” In: Saunders and Whitfield Eds., Biology of Alcohol Problems. 7th ISBRA Congress. Australia. Pergamon Press. New York. pp 157-162.

Seitz, H.K.; Poschl, G. (1997): “Role of gastrointestinal factors in alcohol metabolism.” Alc.Alcoholism: Int. Med. Council Alcoh., 32, 543-549.

Shimizu M. et al. (1990): “Inmunohistochemical of localization of ethanol inducible P450IIE1; alimentary tract.” Gastroenterology, 99, 1044-1053.

Smith, M. E. (1961): “Interrrelations in alcohol and methanol metabolism.” J. Pharm. Exp. Ther., 134, 233-237.

Stryer, L (1995): Bioquímica. 4ª Ed. Reverté, S.A. Barcelona.

Sundberg, M.I.; Tindberg, N. (1998): “Mechanisms of induction of cytochrome P4502E1 in astroglial cells.” 9th ISBRA CONGRESS.Copenhagen, Denmark.

Svensson, S. et al. (1998): “Structural and functional divergence of class II alcohol dehydrogenase: Cloning and characterisation of rabbit liver isoforms of the enzyme.” Europ. J. Biochem., 252, 236-243.

Takada, A. Ed. (1993): “Proceedings of the 13th annual conference of the Japanese Society for Biochemical Research on Alcohol. Osaka. Oxford, UK: Pergamon Press.

Teschker et al. (1975): “Hepatic microsmal alcohol oxidazing system: affinity for methanol, ethanol, propanol and butanol.” J. Biol. Chem., 250, 7397.

Thomasson H.R. et al. (1995): “ADH2 gene polymorphism are determinants of alcohol pharmacokinetics”. Alcohol. Clin. Exp. Res.,19,1494-1499.

Thurman, R.G. et al. (1989): “Swift increase in alcohol metabolism (SIAM): A commentary on the regulation of alcohol metabolism in mamals.” In: Crow, Batt Eds., Human Metabolism of Alcohol. Boca Raton, FL:CRC Press.pp. 17-30.

Tillonen, J. et al. (1998): “Effects of ciprofloxacin on bacteriocolonic pathway for ethanol oxidation in man”. 9th ISBRA CONGRESS.Copenhagen, Denmark.

Topel, H. (1985): “Biochemical basis of alcoholism: Statements and hypotheses of present research.” Alcohol, 2, 711-788.

Vidal, F. et al. (1998): “ Influence of chronic alcohol abuse and liver disease on hepatic aldehyde dehydrogenase activity”. Alcohol, 15, 3-8.

Wall, T.L. (1991): “Electroencephalographic correlates of alcohol-induced flushing in Asian-American men”. Dissert. Abstr. Internat.,52, 2789-B.

Wall, T.L. et al. (1998): “ Self-rating of alcohol´s effects in Asians with aldehyde dehydrogenase (ALDH2) genemutations.” 9th ISBRA CONGRESS.Copenhagen, Denmark.

Wartburg, von J.P. (1979): “The Metabolism of Alcohol in Normals and Alcoholics: Enzymes” In: Kissin and Begleiter, Eds.,The Biology of Alcoholism. Plenum Press. New York. vol 1 pp.63-101

Widmark, E.M.P. (1932): Die theoretischen Grundlagen und die praktische Verwendbarkeit der gerichlich – medizinischen Alkoholbestimmung. Berlin: Urban, Schawarzenberg.

Xie, P. et al. (1997): “X-ray structure of human class IV sigma sigma alcohol dehydrogenase: Structural basis for substrate specificity.” J. Biol. Chem., 272, 18558-18563

Yin, S-J., Li T-K. (1989): “Genetic polymorphism and properties of human alcohol and aldehyde dehydrogenases: implications for ethanol metabolism and toxicity.” In: Sun G.Y.et al. Eds., Molecular Mechanisms of Alcohol. Humana Press. Inc.New Jersey

Yin, S. J. (1998): “Allelic variations of the Alcohol- Dehydrogenases and alcoholism in Asians”. 9th ISBRA CONGRESS. Copenhagen, Denmark.

Yin, S.J. (1994): “Alcohol dehydrogenase: Enzymology and Metabolism.” Alcohol Suppl. 2, 113-119

Yoshida A. et al. (1998): “Human aldehyde dehydrogenase gene family” Eur. J. Biochem., 251, 549-557.

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1999-06-15

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