Parkinson’s disease after psychosurgery for the treatment of cocaine addiction

Authors

  • Alejandro Fuertes-Saiz Universidad Cardenal Herrera-CEU. Consorcio Hospitalario Provincial
  • Mercè Correa Universitat Jaume I
  • John Salamone Universidad de Connecticut
  • Lidia Salais Consorcio Hospitalario Provincial
  • María Teresa Pérez-Saldaña Hospital de Manises
  • Gonzalo Haro Universidad Cardenal Herrera-CEU. Consorcio Hospitalario Provincial

DOI:

https://doi.org/10.20882/adicciones.1614

Keywords:

Cocaine, Parkinson's disease, psychosurgery, side effects, psychoses.

Abstract

In 2018 we published a clinical case (Haro et al., 2018) of a 32-year-old patient who began to use cocaine at the age of 14 and was diagnosed with “limbic dysfunction syndrome” at 17. The treatment recommended by his psychiatrist was psychosurgery. It was performed in two separate interventions in which radiofrequency-induced thermal coagulation lesions were performed with the aim of deactivating the anterior cingulate cortex (AC), disconnecting it from the ventral striatum and the amygdala in both hemispheres. Shortly after the surgery, the patient began to have delusions and was diagnosed with paranoid schizophrenia. At 27 years of age he was showing cognitive deficits and negative psychotic symptoms.With this letter, two years after the first publication of the case, the authors present the evolution of the patient after the appearance of a probable late complication of psychosurgery. New neuroimaging data, neurological evaluation and discussion conducted from a translational point of view are included.

Author Biographies

Alejandro Fuertes-Saiz, Universidad Cardenal Herrera-CEU. Consorcio Hospitalario Provincial

Universidad Cardenal Herrera-CEU, CEU Universities, Castellón. España.Departamento de Salud Mental. Consorcio Hospitalario Provincial, Castellón. España.

Mercè Correa, Universitat Jaume I

Universitat Jaume I, Castellón. España.

John Salamone, Universidad de Connecticut

Universidad de Connecticut, Storrs. EE. UU.

Lidia Salais, Consorcio Hospitalario Provincial

Departamento de Neurología. Consorcio Hospitalario Provincial, Castellón. España.

María Teresa Pérez-Saldaña, Hospital de Manises

Departamento de Neurología. Hospital de Manises. España.

Gonzalo Haro, Universidad Cardenal Herrera-CEU. Consorcio Hospitalario Provincial

Universidad Cardenal Herrera-CEU, CEU Universities, Castellón. España.Departamento de Salud Mental. Consorcio Hospitalario Provincial, Castellón. España.

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Published

2021-03-12

Issue

Section

Letters to the Editors