Cocaine base paste: experience from the Montevideo Poison Control Center
DOI:
https://doi.org/10.20882/adicciones.183Keywords:
cocaine base paste, clinical features, suicide attemptsAbstract
Background: In Uruguay, cocaine base paste (CBP, pasta base) is a widely used form of cocaine. The aim of our study is to determine the main clinical characteristics of CBP abusers. Methods: Retrospective, single-center study of consultations at the Montevideo Poison Control Center between January 1, 2004 and December 31, 2005. Results: One hundred and thirteen consultations were included, with an average age of 22 years (+ − 0.5 years) and a female-male sex ratio of 1:4.3. The consultations were related to drug overdose (77%), suicide attempt (16.8%), and wanting to give up CBP use (6.2%). In 48.1% the time elapsed since inhalation of CBP was less than 6 hours. Doses varied between 0.5 gr. and 25 gr. Use of other drugs at the same time, such as alcohol, marijuana or benzodiazepines, was common (51 cases). The symptoms most frequently observed were neuropsychiatric and cardiovascular, followed by respiratory symptoms. In 16.8% of patients, reason for the consultation was intentional acute ingestion of drugs, considered as a suicide attempt, occurring within a few hours of drug consumption. Discussion: CBP users are mostly young males. Although clinical findings are compatible with those for cocaine abuse, euphoria is a major clinical feature in CBP abusers. The presence of respiratory symptoms reflects the complications associated with the ingestion route. Suicide attempts occurring within a few hours of CBP confirm the high prevalence of suicidal ideation reported by other authors.References
Castaño G. Cocaínas fumables en Latinoamérica. Adicciones 2000; 12:541- 550.
Coca Cultivation and Cocaine Processing: An Overview. Drug Enforcement Administration, Intelligence Division, Strategic Intelligence Section, September 1993. Executive Summary. www.druglibrary.org/schaffer/govpubs/cocccp.htm
Roques Bernard. La Dangerosité des Drogues; 7: La cocaïne; Ed. Odile Jacob, 1999.
Flomenbaum N, Goldfrank L, Hoffman R, Howland, MA; Lewin N;
Nelson L. Goldfrank’s Toxicologic Emergencies, 8th Edition 2006. Part
C: The clinical basis of medical toxicology. Section I – H: Substances of abuse; Chapter 74: Cocaine. Ed McGraw Hill.
Jeri FR, Sánchez CC, del Pozo T, Fernández M, Carbajal C. Further experience with the syndromes produced by coca paste smoking. Bul on Narcotics 1978.
Jeri FR. Coca-paste smoking in some Latin American countries: a severe and unabated form of addiction. Bul on Narcotics 1984.
Pérez J. Clínica de la adicción a pasta base de cocaína. Rev Chil
Neurosiquiatr 2003; 41: 55-63.
Junta Nacional de Drogas. Naciones Unidas, Oficina contra la Droga y el Delito. Pasta base de cocaína. Prácticas y gestión de riesgos en adolescentes uruguayos. Diciembre 2006. http://www.infodrogas.gub.uy/html/material-educativo/documentos/20061207-LibroPastaBase.zip
Dueñas C, Torres CA. Toxicidad pulmonar inducida por cocaína.
Rev Colomb Neumol 1999; 11:45-47.
Tashkin DP, Khalsa ME, Gorelick D, Chang P, Simmons MS, Coulson AH, Gong H Jr: Pulmonary status of habitual cocaine smokers. Am Rev Respir Dis 1992;145:92–100.
Terra Filho M, Yen C, de Paula Santos U, Romero D. Pulmonary
complications in cocaine users. Sao Paulo Med J 2004; 122:26-31.
Pascale A. Toxicidad respiratoria por cocaína [Monografía no publicada]. Departamento de Toxicología. Facultad de Medicina. Montevideo, Uruguay. Año 2009.
