Alcohol consumption, alcohol dependence and related harms in Spain, and the effect of treatment-based interventions on alcohol dependence

Authors

  • Jürgen Rehm Institute for Clinical Psychology and Psychotherapy, TU Dresden, Germany. Department of Psychiatry, University of Toronto, Canada.
  • Maximilien X. Rehm Faculty of Arts and Sciences/Politics and Governance, Ryerson University, Toronto, Canada.
  • Kevin D. Shield Centre for Addiction and Mental Health (CAMH), Toronto, Canada. Institute of Medical Science, University of Toronto, Canada. Contacto: Kevin D. Shield CAMH 33 Russell Street Toronto, Ontario, Canada, M5S 2S1 Phone: +1 647 971 6175 Fax: +1 416 260 4146
  • Gerrit Gmel Centre for Addiction and Mental Health (CAMH), Toronto, Canada.
  • Antoni Gual Alcohol Unit, Psychiatry Dept., Neurosciences Institute, Hospital Clinic, IDIBAPS, Barcelona, Spain.

DOI:

https://doi.org/10.20882/adicciones.67

Keywords:

Alcohol, dependence, mortality, treatment, Spain

Abstract

Alcohol consumption in Spain has traditionally followed the Mediterranean drinking pattern, featuring daily drinking with meals, beer as the preferred beverage, and comparatively little drinking to intoxication. Alcohol depen- dence (AD), one of the most detrimental disorders caused by alcohol, was prevalent in 0.2% of women and 1.2% of men, corresponding to 31,200 women and 186,000 men in Spain with AD in 2005 in the age group of 15 to 64 year. These prevalence estimates of alcohol dependence are likely underestimated due to limitations in the World Mental Health Survey which cannot be fully corrected for; however, the estimates of AD for Spain represent the most accurate and up to date estimates available. Alcohol creates a significant health burden in Spain with 11.3 premature deaths in women per 100,000 aged 15 to 64 years, and 40.9 premature deaths in men per 100,000 in the same age group were due to alcohol consumption (data for 2004). This amounts to 8.4% of all female deaths and 12.3% of all the male deaths in this age group being attributable to alcohol consum-ption. A large percentage of these harms were due to heavy alcohol consumption and AD.AD is undertreated in Spain, with less than 10% of all people with AD trea- ted. For those who are treated, psychotherapy is the most utilized form of treatment to avoid relapse. If 40% of AD patients in Spain were treated with pharmacological treatment (the most effective treatment method), 2.2% of female and 6.2% of male deaths due to AD would be prevented within one year. Thus by increasing treatment rates is an important means of reducing the alcohol-attributable mortality and health burden in Spain.

References

Cherpitel, C. Alcohol and casualties: a comparison of emergency room and coroner data. (1994). Alcohol and Alcoholism, 29 211-218.

Cherpitel, C. Alcohol in fatal and nonfatal injuries: a comparison of

coroner and emergency room data from the same country. (1996).

Alcoholism: Clinical and Experimental Research, 20(2), 338-342.

Corrao, G., Rubbiati, L., Bagnardi, V., Zambon, A., y Poikolainen, K.

Alcohol and coronary heart disease: A meta-analysis. (2000). Addiction, 95(10), 1505-1523.

Gmel, G. Jr., Shield, K. D., Frick, H., Kehoe, T., Gmel, G., y Rehm, J.

Estimating uncertainty of alcohol-attributable fractions for infectious and chronic diseases. (2011). BMC Med Res Methodol, 1148.

Harvard University, Institute for Health Metrics and Evaluation, John Hopkins University, University of Queensland, y World Health Organization. (2010) Global Burden of Diseases, Injuries, and Risk Factors Study (GBD 2005 Study) Operations manual. Seattle, WA: Institute for Health Metrics and Evaluation.

Laslett, A. M., Catalano, P., Chikritzhs, T., Dale, C., Doran, C., Ferris, J. et al. (2010) The range and magnitude of alcohol’s harm to others. Fitzroy, Vic: Turning Point Alcohol & Drug Centre.

Lopez, A. D., Mathers, C. D., Ezzati, M., Jamison, D. T., y Murray, C. J.

L. Global and regional burden of disease and risk factors, 2001:Systematic analysis of population health data. (2006). Lancet, 367(9524), 1747-1757.

Lopez, A. D., Mathers, C. D., Ezzati, M., Jamison, D. T., y Murray, C. J.

L. (2006) Global burden of disease and risk factors. New York & Washington: The World Band and Oxford University Press.

Murray, C. J. L.,y Lopez, A. Global mortality, disability, and the

contribution of risk factors: global burden of disease study. (1997).

Lancet, 349 1436-1442.

Puddey, I. B., Rakic, V., Dimmitt, S. B., y Beilin, L. J. Influence of pattern of drinking on cardiovascular disease and cardiovascular risk factors - a review. (1999). Addiction, 94 649-663.

R Development Core Team. (2011) R: A Language and Environment for

Statistical Computing (version 2.13.0). Vienna, Austria: R Foundation

for Statistical Computing.

Rehm, J., Baliunas, D., Borges, G. L. G., Graham, K., Irving, H. M., Kehoe,

T. et al. The relation between different dimensions of alcohol consumption and burden of disease - An overview. (2010). Addiction, 105(5), 817-843.

Rehm, J., Sempos, C., y Trevisan, M. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease - a review. (2003). Journal of Cardiovascular Risk, 10(1), 15-20.

Roerecke, M.,y Rehm, J. Irregular heavy drinking occasions and risk of

ischemic heart disease: a systematic review and meta-analysis. (2010). American Journal of Epidemiology, 171(6), 633-644.

Roerecke, M.,y Rehm, J. The cardioprotective association of average alcohol consumption and ischaemic heart disease: a systematic review and meta-analysis. (2012). Addiction, 107(7), 1246-1260.

Ronksley, P. E., Brien, S. E., Turner, B. J., Mukamal, K. J., y Ghali, W. A.

Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. (2011).BMJ, 342 d671.

Rothman, K. J., Greenland, S., y Lash, T. L. (2008) Modern Epidemiology, 3rd ed. PA, USA: Lippincott Williams & Wilkins.

Taylor, B., Shield, K., y Rehm, J. Combining best evidence: A novel method to calculate the alcohol-attributable fraction and its variance for

injury mortality. (2011). BMC Public Health, 11(1), 265.

United Nations Population Division. (2007) World Population Prospects -

The 2006 revision. New York: United Nations.

United Nations Population Division. (2009) World population prospectsthe

revision. New York: United Nations.

Baan, R., Straif, K., Grosse, Y., Secretan, B., El Ghissassi, F., Bouvard, V. et al. Carcinogenicity of alcoholic beverages. (2007). Lancet Oncology,

(4), 292-293.

Baliunas, D., Taylor, B., Irving, H., Roerecke, M., Patra, J., Mohapatra, S. et al. Alcohol as a risk factor for type 2 diabetes - A systematic review

and meta-analysis. (2009). Diabetes Care, 32(11), 2123-2132.

Corrao, G., Bagnardi, V., Zambon, A., y La Vecchia, C. A meta-analysis of

alcohol consumption and the risk of 15 diseases. (2004). Preventive

Medicine, 38 613-619.

Gmel, G., Shield, K., y Rehm, J. Developing a methodology to derive

alcohol-attributable fractions for HIV/AIDS mortality based on alcohol’s impact on adherence to antiretroviral medication. (2011). Population Health Metrics, 9(1), 5.

International Agency for Research on Cancer. (2010) Alcoholic beverage

consumption and ethyl carbamate (urethane). IARC Monograph 96 on the

Evaluation of Carcinogenic Risks to Humans. Lyon, France: International

Agency for Research on Cancer (IARC).

Irving, H. M., Samokhvalov, A., y Rehm, J. Alcohol as a risk factor for

pancreatitis. A systematic review and meta-analysis. (2009). Journal

of the Pancreas, 10(4), 387-392.

Lönnroth, K., Williams, B., Stadlin, S., Jaramillo, E., y Dye, C. Alcohol use

as a risk factor for tuberculosis - a systematic review. (2008). BMC

Public Health, 8 289.

Patra, J., Taylor, B., Irving, H., Roerecke, M., Baliunas, D., Mohapatra, S.

et al. Alcohol consumption and the risk of morbidity and mortality from different stroke types - a systematic review and meta-analysis.

(2010). BMC Public Health, 10(1), 258.

Patra, J., Bakker, R., Irving, H., Jaddoe, V. W. V., Malini, S., y Rehm, J.

Dose-response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA)-a systematic review and meta-analyses. (2011). BJOG: International Journal of Obstetrics and Gynaecology, 118(12), 1411-1421.

Rehm, J., Kehoe, T., Gmel, G., Stinson, F., Grant, B., y Gmel, G. Statistical

modeling of volume of alcohol exposure for epidemiological studies of population health: the example of the US. (2010). Population Health Metrics, 8 3.

Rehm, J., Mathers, C., Popova, S., Thavorncharoensap, M., Teerawattananon, Y., y Patra, J. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol use disorders. (2009). Lancet, 373(9682), 2223-2233.

Roerecke, M.,y Rehm, J. Irregular heavy drinking occasions and risk of

ischemic heart disease: a systematic review and meta-analysis. (2010). American Journal of Epidemiology, 171(6), 633-644.

Roerecke, M.,y Rehm, J. The cardioprotective association of average alcohol consumption and ischaemic heart disease: a systematic review and meta-analysis. (2012). Addiction, [Epub ahead of print].

Samokhvalov, A. V., Irving, H., Mohapatra, S., y Rehm, J. Alcohol

consumption, unprovoked seizures and epilepsy: a systematic review and meta-analysis. (2010). Epilepsia, 51(7), 1177-1184.

Samokhvalov, A. V., Irving, H. M., y Rehm, J. Alcohol as a risk factor for

atrial fibrillation: a systematic review and meta-analysis. (2010a).

European Journal of Cardiovascular Prevention & Rehabilitation, 17(6),

-712.

Samokhvalov, A. V., Irving, H. M., y Rehm, J. Alcohol consumption as

a risk factor for pneumonia: systematic review and meta-analysis.

(2010b). Epidemiology and Infection, 138(12), 1789-1795.

Taylor, B., Irving, H. M., Baliunas, D., Roerecke, M., Patra, J., Mohapatra,

S. et al. Alcohol and hypertension: gender differences in doseresponse

relationships determined through systematic review and meta-analysis. (2009). Addiction, 104(12), 1981-1990.

Taylor, B., Irving, H. M., Kanteres, F., Room, R., Borges, G., Cherpitel, C.

et al. The more you drink, the harder you fall: a systematic review

and meta-analysis of how acute alcohol consumption and injury or

collision risk increase together. (2010). Drug and Alcohol Dependence,

(1-2), 108-116.

Taylor, B., Shield, K., y Rehm, J. Combining best evidence: A novel method to calculate the alcohol-attributable fraction and its variance for

injury mortality. (2011). BMC Public Health, 11(1), 265.

Corrao, G., Bagnardi, V., Zambon, A., y La Vecchia, C. A meta-analysis of

alcohol consumption and the risk of 15 diseases. (2004). Preventive

Medicine, 38 613-619.

Cuijpers, P., Riper, H., y Lemmers, L. The effects on mortality of brief

interventions for problem drinking: a meta-analysis. (2004). Addiction,

(7), 839-845.

De Lorenze, G. N., Weisner, C., Tsai, A. L., Satre, D. D., y Quesenberry, C. P. J. Excess mortality among HIV-infected patients diagnosed with

substance use dependence or abuse receiving care in a fully integrated

medical care program. (2011). Alcoholism: Clinical and Experimental

Research, 35(2), 203-210.

Harris, E. C.,y Barraclough, B. Excess mortality of mental disorder. (1998).

British Journal of Psychiatry, 173 11-53.

Magill, M.,y Ray, L. A. Cognitive-behavioral treatment with adult alcohol

and illicit drug users: ameta-analysis of randomized controlled trials. (2009). J Stud Alcohol Drugs, 70(4), 516-527.

McQueen, J., Howe, T. E., Allan, L., Mains, D., y Hardy, V. Brief interventions for heavy alcohol users admitted to general hospital wards. (2011). Cochrane Database of Systematic Reviews, 8 CD005191.

O’Brien, J. M. J., Lu, B., Ali, N. A., Martin, G. S., Aberegg, S. K., Marsh, C. B. et al. Alcohol dependence is independently associated with sepsis, septic shock, and hospital mortality among adult intensive care unit patients. (2007). Critical Care Medicine, 35(2), 345-350.

Project MATCH Research Group. Matching alcoholism treatment to client heterogeneity: Project MATCH posttreatment drinking outcomes. (1997). Journal of Studies on Alcohol, 58 7-30.

Room, R., Babor, T., y Rehm, J. Alcohol and public health: a review(2005). Lancet, 365 519-530.

Rösner, S., Hackl-Herrwerth, A., Leucht, S., Lehert, P., Vecchi, S., y Soyka,

M. Acamprosate for alcohol dependence. (2010a). Cochrane Database of Systematic Reviews, 9 CD004332.

Rösner, S., Hackl-Herrwerth, A., Leucht, S., Vecchi, S., Srisurapanont, M.,

y Soyka, M. Opioid antagonists for alcohol dependence. (2010b). Cochrane Database of Systematic Reviews, 12 CD001867.

Smedslund, G., Berg, R. C., Hammerstrom, K. T., Steiro, A., Leiknes, K.A.,

Dahl, H. M. et al. Motivational interviewing for substance abuse.

(2011). Cochrane Database of Systematic Reviews, 5 CD008063.

Kehoe, T., Gmel, G. j., Shield, K., Gmel, G. s., y Rehm, J. Modelling alcohol

consumption as a distribution and determining the impact of the distribution on estimated alcohol-attributable harms. (2012).

Population Health Metrics, 10(1), 6.

Rehm, J., Kehoe, T., Gmel, G., Stinson, F., Grant, B., y Gmel, G. Statistical

modeling of volume of alcohol exposure for epidemiological studies

of population health: the example of the US. (2010). Population Health Metrics, 8 3.

Published

2013-03-01

Issue

Section

Originals