Psychiatric morbidity among cocaine and heroin users in the community

Authors

  • Silvia Tortajada CIBER en Epidemiología y Salud Pública (CIBERESP).
  • Mª Jesús Herrero Drug Abuse Epidemiology Research Group. IMIM-Hospital del Mar.
  • Antònia Domingo-Salvany CIBER en Epidemiología y Salud Pública (CIBERESP). Drug Abuse Epidemiology Research Group. IMIM-Hospital del Mar. Enviar correspondencia a: Antònia Domingo-Salvany Grup de Recerca en Epidemiologia de les Drogues d’Abús. IMIM-Hospital del Mar. Dr Aiguader 88. E-08003. Barcelona, Spain Phone: 34 933160757 - Fax 34 933160797
  • Gemma Molist CIBER en Epidemiología y Salud Pública (CIBERESP). Centro Nacional de Epidemiología. Instituto de Salud Carlos III.
  • Gregorio Barrio CIBER en Epidemiología y Salud Pública (CIBERESP). Centro Nacional de Epidemiología. Instituto de Salud Carlos III.
  • Luís De La Fuente CIBER en Epidemiología y Salud Pública (CIBERESP). Centro Nacional de Epidemiología. Instituto de Salud Carlos III.
  • Mª Teresa Brugal CIBER en Epidemiología y Salud Pública (CIBERESP). Agència de Salut Pública de Barcelona (ASPB).

DOI:

https://doi.org/10.20882/adicciones.91

Keywords:

cocaine, heroin, CIDI, psychiatric morbidity, young population

Abstract

Drug abuse is a serious public health problem. Moreover, co-occurringmental health and substance abuse disorders are common among drugusers. This paper examines psychiatric disorders of young cocaine andheroin users using the World Mental Health Composite InternationalDiagnostic Interview (WMH-CIDI).A cohort of 1266 young (18-30 years) current regular cocaine (705)and heroin (561) users were recruited outside the health services inBarcelona, Madrid and Seville, Spain. The WMH-CIDI was used toevaluate mental disorders; the Severity of Dependence Scale (SDS)measured the degree of dependence; and the Duke-UNC FunctionalSocial Support Questionnaire (FSSQ) assessed social support, in a crosssectional study design.About 43% was diagnosed with a lifetime mental disorder. The mostcommon diagnoses were depression (37.5%) and specific phobia (6.8%).During the last 12 months, prevalence rates were also slightly higher inheroin group (26.4%) than in cocaine cohort (21.7%). Every day cocaineconsumption, having unstable living conditions and low social supportwere variables highly associated with psychiatric morbidity in cocainecohort. In heroin cohort, earning money through illegal activitieswas associated with psychiatric morbidity, while the moderate use ofalcohol acted as a protective factor for mental pathology. Morbiditywas associated to having received psychiatric/psychological treatmentduring the last 12 months in both cohorts.This study has shown a relatively high prevalence of psychiatricmorbidity in cocaine and heroin users recruited in non-clinical settings.Future studies examining differences between cocaine and heroinpatterns of consumption associated with mental diseases are necessary.

References

Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H.,… Vollebergh. W. A. (2004). Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatrica Scandinavica, 109, 21-27.

Alonso, J., Ferrer, M., Romera, B., Vilagut, G., Argermeyer, M., Bernert,

S.,… McColgen, Z. (2002). The European study of the epidemiology of mental disorders (ESEMeD/MHEDEA 2000) Project: rationale and methods. International Journal of Methods in Psychiatric Research, 11, 55-67.

Alonso, J. & Lepine, J. P. (2007). Overview of Key Data From the European

Study of the Epidemiology of Mental Disorders (ESEMeD). Journal of Clinical Psychiatry, 68, 3-9.

Alvarez-Ude, F., Valdes, C., Estebanez, C. & Rebollo, P. (2004). Healthrelated quality of life of family caregivers of dialysis patients.

Journal of Nephrology, 17, 841-850.

Andrews, G., Slade, T. & Issakidis, C. (2002). Deconstructing current

comorbidity: data from the Australian National Survey of Mental Health and Well-Being. British Journal of Psychiatry, 181, 306-314.

Bellon Saameno, J. A., Delgado, S. A., Luna del Castillo, J. D. & Lardelli,

C. P. (1996). Validez y fiabilidad del cuestionario de apoyo social funcional Duke-UNC-11. Atencion Primaria, 18, 153-163.

Brady, K. T. & Randall, C. L. (1999). Gender differences in substance use

disorders. Psychiatric Clinics of North America, 22, 241-252.

Broadhead, W. E., Gehlbach, S. H., de Gruy, F. V. & Kaplan, B. H.

(1988). The Duke-UNC Functional Social Support Questionnaire.

Measurement of social support in family medicine patients. Medical Care, 26, 709-723.

Casares-Lopez, M. J., Gonzalez-Menendez, A., Bobes-Bascaran, M. T.,

Secades, R., Martinez-Cordero, A. & Bobes, J. (2011). Need for the

assessment of dual diagnosis in prisons. Adicciones, 23, 37-44.

Compton, W. M., III, Cottler, L. B., Ben Abdallah, A., Phelps, D. L.,

Spitznagel, E. L. & Horton, J. C. (2000). Substance dependence and

other psychiatric disorders among drug dependent subjects: race and gender correlates. The American Journal on Addictions, 9, 113-125.

Compton, W. M., Thomas, Y. F., Conway, K. P. & Colliver, J. D. (2005).

Developments in the epidemiology of drug use and drug use disorders. American Journal of Psychiatry, 162, 1494-1502.

Cox, J. E., Buman, M., Valenzuela, J., Joseph, N. P., Mitchell, A. & Woods,

E. R. (2008). Depression, parenting attributes, and social support among adolescent mothers attending a teen tot program. Journal of Pediatric and Adolescent Gynecology, 21, 275-281.

de Girolamo, G., Polidori, G., Morosini, P., Mazzi, F., Serra, G., Scarpino,

V.,… Rossi, A. (2005). [Prevalence of common mental disorders in Italy, risk factors, health status, and utilization of health services: the ESEMeD-WMH project]. Epidemiologia e Psichiatria Sociale, 14, 1-100.

de la Fuente, L., Brugal, M. T., Ballesta, R., Bravo, M. J., Barrio, G.,

Domingo-Salvany, A.,… Ambros, M. (2005). Metodología del estudio de cohortes del proyecto ITINERE sobre consumidores de heroína en tres ciudades españolas y características básicas de los participantes. Revista Española de Salud Pública, 79, 475-491.

Del Boca, F. K. & Darkes, J. (2003). The validity of self-reports of alcohol

consumption: state of the science and challenges for research. Addiction, 98, 1-12.

Feinstein, A. R. (1970). The pre-therapeutic classification of co-morbidity

in chronic disease. Journal of Chronic Diseases, 23, 455-469.

Gonzalez-Saiz, F. & Salvador-Carulla, L. (1998). Estudio de fiabilidad y

validez de la versión española de la escala Severity of Dependence Scale (SDS) [Fiability and validity Study of Spanish version of Severity of Dependence Scale (SDS)]. Adicciones, 10, 223-232.

Gossop, M., Best, D., Marsden, J. & Strang, J. (1997). Test-retest reliability

of the Severity of Dependence Scale. Addiction, 92, 353.

Grant, B. F., Stinson, F. S., Dawson, D. A., Chou, S. P., Dufour, M. C.,

Compton, W.,… Kaplan, K. (2004). Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Archives of General Psychiatry, 61, 807-816.

Haro, J. M., Arbabzadeh-Bouchez, S., Brugha, T. S., de Girolamo, G.,

Guyer, M. E., Jin, R.,… Kessler, R. C. (2006). Concordance of the

Composite International Diagnostic Interview Version 3.0 (CIDI 3.0)

with standardized clinical assessments in the WHO World Mental

Health surveys. International Journal of Methods in Psychiatric Research, 15, 167-180.

Hartnoll, R., Griffits, P., Taylor, C., Hendrick, V., Blanken, P., & Nolimal,

D. (1997). Handbook on snowball sampling. Strasbourg: Pompidou

Group, Council of Europe.

Herrero, M. J., Domingo-Salvany, A., Brugal, M. T. & Torrens, M. (2011).

Incidence of psychopathology in a cohort of young heroin and/ or cocaine users. Journal of Substance Abuse and Treatment, 41, 55-63.

Herrero, M. J., Domingo-Salvany, A., Torrens, M., Brugal, M. T. & and the

ITINERE Investigators. (2008). Psychiatric comorbidity in young cocaine users: induced versus independent disorders. Addiction, 103, 284-293.

Kerr, W. C., Greenfield, T. K., Bond, J., Ye, Y. & Rehm, J. (2011). Racial and ethnic differences in all-cause mortality risk according to alcohol

consumption patterns in the national alcohol surveys. American Journal of Epidemiology, 174, 769-778.

Kessler, R. C., Chiu, W. T., Demler, O., Merikangas, K. R. & Walters, E. E.

(2005). Prevalence, severity, and comorbidity of 12-month DSM-IV

disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62, 617-627.

Kessler, R. C. & Ustun, T. B. (2004). The World Mental Health (WMH)

Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI). International

Journal of Methods in Psychiatric Research, 13, 93-121.

Krueger, R. F., Chentsova-Dutton, Y. E., Markon, K. E., Goldberg, D. & Ormel, J. (2003). A cross-cultural study of the structure of comorbidity among common psychopathological syndromes in the general health care setting. Journal of Abnormal Psychology, 112, 437-447.

Lahuerta, C., Borrell, C., Rodriguez-Sanz, M., Perez, K. & Nebot, M. (2004). [The influence of the social network on mental health in the

elderly]. Gaceta Sanitaria, 18, 83-91.

Malta, M., Strathdee, S. A., Magnanini, M. M. & Bastos, F. I. (2008).

Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review. Addiction, 103, 1242-1257.

Newman, J. C., Des, J., Turner, C. F., Gribble, J., Cooley, P. & Paone, D.

(2002). The differential effects of face-to-face and computer interview modes. American Journal of Public Health, 92, 294-297.

NOVA Research Company (2002). Questionnaire Development System

0 (QDSTM). [Computer software]. Bethesda, NOVA Research Company..

Pavarin, R. M. (2006). Substance use and related problems: a study on

the abuse of recreational and not recreational drugs in Northern Italy. Annali dell Istituto Superiore di Sanita, 42, 477-484.

Pulido, J., Teresa, B. M., de la, F. L., Ballesta, R., Barrio, G., Bravo, M. J.,…

Fernandez, F. (2009). [Recruitment methodology and characteristics of a cohort of young regular cocaine users in three Spanish cities (the Itinere-cocaine Project).]. Gaceta Sanitaria, 23, 200-207.

Rehm, J. (1998). Measuring quantity, frequency, and volume of drinking.

Alcoholism-Clinical and Experimental Research , 22, 4S-14S.

Robins, L. N., Wing, J., Wittchen, H. U., Helzer, J. E., Babor, T. F., Burke,

J.,… Regier, D. A. (1988). The Composite International Diagnostic Interview. An epidemiologic Instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Archives of General Psychiatry, 45, 1069-1077.

Rodgers, B., Korten, A. E., Jorm, A. F., Jacomb, P. A., Christensen, H. &

Henderson, A. S. (2000). Non-linear relationships in associations of depression and anxiety with alcohol use. Psychological Medicine, 30, 421-432.

Rodriguez-Llera, M. C., Domingo-Salvany, A., Brugal, M. T., Silva, T. C.,

Sanchez-Niubo, A. & Torrens, M. (2006). Psychiatric comorbidity in young heroin users. Drug and Alcohol Dependence, 84, 48-55.

Roncero, C., Daigre, C., Gonzalvo, B., Valero, S., Castells, X., Grau-Lopez,

L.,… Casas, M. (in press). Risk factors for cocaine-induced psychosis in cocaine-dependent patients. European Psychiatry.

Rounsaville, B. J. (2004). Treatment of cocaine dependence and depression. Biological Psychiatry, 56, 803-809.

Rush, B., Urbanoski, K., Bassani, D., Castel, S., Wild, T. C., Strike, C.,…

Somers, J. (2008). Prevalence of co-occurring substance use and other mental disorders in the Canadian population. Canadian Journal of Psychiatry, 53, 800-809.

Stein, D. J., Seedat, S., Herman, A., Moomal, H., Heeringa, S. G., Kessler,

R. C. & Williams D. R. (2008). Lifetime prevalence of psychiatric disorders in South Africa. The British Journal of Psychiatry, 192, 112-117.

Szerman, N., Arias, F., Vega, P., Babín, F., Mesías, B., Basurte, I.,… Poyo,

F. (2011). Pilot study on the prevalence of dual pathology in community mental health and substance misuse services in Madrid. Adicciones, 23, 249-255.

Szerman, N., Lopez-Castroman, J., Arias, F., Morant, C., Babin, F., Mesias,

B.,… Baca-Garcia, E. (2012). Dual diagnosis and suicide risk in a Spanish outpatient sample. Substance Use and Misuse, 47, 383-389.

Tait, R. J. & Hulse, G. K. (2006). Hospital morbidity and alcohol consumption in less severe psychiatric disorder: 7-year outcomes. The British Journal of Psychiatry, 188, 554-559.

Torrens, M., Gilchrist, G. & Domingo-Salvany, A. (2011). Psychiatric comorbidity in illicit drug users:substance induced versus independent disorders. Drug and Alcohol Dependence, 113, 147-156.

Turner, C. F., Ku, L., Rogers, S. M., Lindberg, L. D., Pleck, J. H. & Sonenstein, F. L. (1998). Adolescent sexual behavior, drug use, and violence: increased reporting with computer survey technology. Science, 280, 867-873.

van Os, J., Bak, M., Hanssen, M., Bijl, R. V., de Graaf, R. & Verdoux, H.

(2002). Cannabis use and psychosis: a longitudinal populationbased study. American Journal of Epidemiology, 156, 319-327.

Watters, J. K. & Biernacki, P. (1989). Targeted sampling: options for the

study of hidden populations. Social Problems, 36, 416-430.

Williams, D. R., Herman, A., Stein, D. J., Heeringa, S. G., Jackson, P. B.,

Moomal, H. & Kessler, R. C. (2008). Twelve-month mental disorders in South Africa: prevalence, service use and demographic correlates in the population-based South African Stress and Health Study. Psychological Medicine, 38, 211-220.

Wittchen, H. U. (1994). Reliability and validity studies of the WHO- -Composite International Diagnostic Interview (CIDI): a critical review. Journal of Psychiatric Research, 28, 57-84.

Zilberman, M., Tavares, H. & el Guebaly, N. (2003). Gender similarities

and differences: the prevalence and course of alcohol- and other substance-related disorders. Journal of Addictive Disorders, 22, 61-74.

Published

2012-09-01

Issue

Section

Originals